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Education; biotechnology; bioprocess design; modeling and simulation; scale-up
Abstract
Delft University of Technology offers Engineering Doctorate (EngD) programmes in Bioprocess Engineering, aiming at the translation of academic developments into real-life applications. These two-year salaried design traineeships offer an application-focused alternative to traditional PhD positions, and provide trainees with a solid basis for an accelerated start in an industrial career.
A very strong engineering background for the Designer in Bioprocess EngD programme is requested: mathematics, mass and heat transfer, and experience with modeling and simulation software tools. In the first year of the programme, the EngD designers follow a dedicated curriculum involving relevant courses, interactive workshops, and group design assignments in close cooperation with industrial partners. In the second year, they perform their Individual Design Project, typically seconded within a company, working on real business cases covering from small start-ups to large multinational companies in the biobased, biopharmaceutical, food, cosmetics, bioplastics, and wastewater sectors, among others. In addition to technological topics, the participants acquire professional skills in areas such as stakeholder management, personal and project management, and communication.
Our industrial partners, on the other hand, benefit from fully supported collaborations delivering a fit-for-purpose (tailor-made) design project at a competitive cost, executed by one or more of our selected trainees under he supervision of TU Delft’s principal investigators and experts, plus an experienced design coach. Examples of previous design assignments are:
- Downstream process development for a novel single cell protein production technology
- Raman-based chemometric model development for mammalian cell culture production
- Techno-economic feasibility of a chromatographic process to obtain a concentrated stream of antibodies from dairy products
- Evaluation of continuous manufacturing for enzyme production
- Continuous processing of food bio-chemicals: development of a CFD model for protein concentration via ultrafiltration
- Bio-based platform chemicals: sequential screening & selection of technical options
Besides promoting collaboration and fostering knowledge and technology transfer between academia and industry, our industrial partners additionally become part of the academic network of TU Delft and other TU Delft-wide initiatives, such as the Delft Process & Product Technology Institute and Delft Bioengineering Institute, furthering academic-industry initiatives for a sustainable future.
References
- www.tudelft.nl/engd
